I'm not sure that anybody's really going to see this so far into the topic, but you should pop on a pair of latex gloves just before you pop the fuel lines off the filter.
There is some nasty stuff in the fuel, and even if the lines are no longer pressurized, some gas will spill out of the filter. It's been a while since I looked at the MSDS for gasoline, but words toluene and benzene come to mind.